Medications


hyaluronidase-oysk/trastuzumab Injectable Solution 2000 units/120 mg per mL (5 mL)

Uses

For treating cancer.

Instructions

This medicine is used by injecting it into the skin. Please ask your doctor, nurse or pharmacist for the correct places on your body where this medicine can be injected.

This medicine should be given over 2-5 minutes.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Please tell your doctor and pharmacist about all the medicines you take. Include both prescription and over-the-counter medicines. Also tell them about any vitamins, herbal medicines, or anything else you take for your health.

Your doctor may prescribe other medications to reduce side effects. Follow instructions carefully.

Pain or fever reducers may relieve some side effects. Please speak with your healthcare provider or pharmacist.

Use effective birth control to avoid pregnancy.

It is very important that you keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine. Symptoms of an allergic reaction can include trouble breathing, skin rash, itching, swelling, or severe dizziness.

Some patients with weak hearts may have worsening of symptoms. If you notice difficulty breathing, weight gain, or swelling of your legs or ankles, let your doctor know right away.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

This medicine may reduce your body's ability to fight infections. Try to avoid contact with people with colds, flu or other infections.

Contact your doctor if you develop any signs of a new infection such as fever, cough, sore throat, or chills.

Wash your hands often and avoid close contact with people with infections such as colds and flu.

Speak with your health care provider before receiving any vaccinations.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not breastfeed while on this medicine. You may safely start breastfeeding 7 months after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women must use reliable forms of birth control while taking this medicine and for 7 months after stopping to prevent pregnancy.

Ask your pharmacist if this medicine can interact with any of your other medicines. Be sure to tell them about all the medicines you take.

Please tell all your doctors and dentists that you are on this medicine before they provide care.

Do not start or stop any other medicines without first speaking to your doctor or pharmacist.

This medicine should be used with caution in patients with breathing difficulties.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • pain in the abdomen
  • decreased appetite
  • diarrhea
  • headaches
  • high blood pressure
  • reaction at the area of the injection (pain, redness, swelling)
  • pain in the joints
  • mouth sores or irritation
  • muscle pain
  • nausea
  • vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • bone pain
  • wheezing or difficulty breathing
  • chest pain
  • confusion
  • weakened heart; fluid in lungs
  • cough that does not go away
  • dizziness
  • swelling of the face, mouth, tongue or throat
  • swelling of the legs, feet, and hands
  • fever or chills
  • fast or irregular heart beats
  • mood changes
  • feeling of numbness or tingling in your hands and feet
  • shortness of breath
  • red, peeling or blistering skin
  • unusual or unexplained tiredness or weakness
  • blurring or changes of vision
  • weakness on one side of the body
  • sudden or unexplained weight gain

A few people may have an allergic reactions to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Extra

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it.Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions.Always follow their advice. There is a more complete description of this medicine available in English.Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.


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