Orkambi Oral Granules 125 mg/100 mg
For cystic fibrosis.
Mix the medicine in a small amount of liquid or soft food and then swallow it.
Use only liquids or soft foods at or below room temperature to mix the medicine. Do not use hot liquid or food.
After mixing the medicine, use it within 1 hour. Throw away any leftover medicine. Do not save for later use.
Take with a high fat food.
It is very important that you take the medicine at about the same time every day. It will work best if you do this.
Store at room temperature in a dry place. Do not keep in the bathroom.
Keep the medicine away from heat and light.
Shake the bottle well before using the medicine.
Avoid grapefruit juice while on this medicine.
It is important that you keep taking each dose of this medicine on time even if you are feeling well.
If you forget to take a dose on time, take it as soon as you remember. If it is less than 6 hours to the next dose, do not take the missed dose. Return to your normal dosing schedule. Do not take 2 doses of this medicine at one time.
Please tell your doctor and pharmacist about all the medicines you take. Include both prescription and over-the-counter medicines. Also tell them about any vitamins, herbal medicines, or anything else you take for your health.
If your symptoms do not improve or they worsen while on this medicine, contact your doctor.
The foods you eat can change how well this medicine works. Tell your doctor about the types of food you normally eat. Ask your doctor for a list of foods that can affect this medicine. Do not significantly change the foods you normally eat while on this medicine.
Do not suddenly stop taking this medicine. Check with your doctor before stopping.
This medicine may decrease the effectiveness of some birth controls which use hormones (such as birth control pills and patches). Use an extra form of birth control, such as condoms, while on this medicine.
It is very important that you keep all appointments for medical exams and tests while on this medicine.
Do not take the medicine more than twice during 24 hours.
Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine. Symptoms of an allergic reaction can include trouble breathing, skin rash, itching, swelling, or severe dizziness.
This medicine is associated with a rare but very serious medical condition. Please speak with your doctor about symptoms you should look out for while on this medicine. Notify your doctor immediately if you develop those symptoms.
Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.
This medicine has been associated with a rare but serious skin rash. If you notice any red, peeling or blistered skin, contact your doctor immediately.
This medicine is associated with a rare, but serious problem of the liver. Speak to your doctor about the early signs of liver problems and the benefits and risks of using this medicine.
Do not use the medication any more than instructed.
If possible, avoid using with marijuana or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.
Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.
Please check with your doctor before drinking alcohol while on this medicine.
If you drink more than a few alcoholic beverages each day, ask your doctor whether you should be on this medicine.
Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.
Do not take St. John's wort while on this medicine.
Ask your pharmacist if this medicine can interact with any of your other medicines. Be sure to tell them about all the medicines you take.
Please tell all your doctors and dentists that you are on this medicine before they provide care.
Do not start or stop any other medicines without first speaking to your doctor or pharmacist.
This medicine should be used with caution in patients with breathing difficulties.
Call your doctor right away if you notice slow or shallow breathing.
Do not share this medicine with anyone who has not been prescribed this medicine.
Always refill this medicine before it runs out.
The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.
Call your doctor or get medical help right away if you notice any of these more serious side effects:
- chest pain
- severe, watery or bloody diarrhea
- high blood pressure
- symptoms of liver damage (such as yellowing of skin or eyes, dark urine, unusual tiredness or weakness; severe stomach or back pain)
- skin irritation such as redness, itching, rash, or burning
- shortness of breath
- blurring or changes of vision
- severe or persistent vomiting
- worsening breathing symptoms
A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.
Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.https://krames.meducation.com/V2.0/fdbpem/1715
IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all
there is to know about it.Your doctor or pharmacist may give you other documents about your medicine.
Please talk to them if you have any questions.Always follow their advice. There is a more complete
description of this medicine available in English.Scan this code on your smartphone or tablet or use
the web address below. You can also ask your pharmacist for a printout. If you have
any questions, please ask your pharmacist.